Although cefazolin isn't approved for use in dogs by the US Food and Drug Administration, veterinarians are allowed to prescribe it "off-label" for use in their patients. This medication combats various bacterial infections, especially gram-positive bacteria such as staphylococcus and streptococcus. While usually given intravenously, it's available in a solution as ear drops for bacterial ear infections.
Some dogs experience diarrhea and vomiting after receiving cefazolin, especially after intravenous administration. The drug shouldn't be mixed in an intravenous line with any other medications. Since it can interact with other medications, tell your vet about any drugs your dog receives, whether prescription or over the counter. The latter includes vitamin B preparations. Dogs with kidney disease shouldn't receive cefazolin.
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