One may be big and one may be extra small, but as long as the parties involved aren't neutered, a German shepherd can mate with a Chihuahua. You may have your eye on a potential partner for your dog, but before you set up a date, there are a few considerations to take into account.
Big Mothers Wanted
There's no catchy name for a German shepherd crossbred with a Chihuahua, although they can certainly make puppies together. If your Chihuahua is a female, she should mate with a guy closer to her own size. A male German shepherd will father pups that are too large for your little Chihuahua lady to birth -- the size of the puppies typically falls somewhere in between the two dogs sizes. Consider a German shepherd tends to be 22 to 26 inches tall at the shoulder and weigh 50 to 90 pounds, and a Chihuahua maxes out at 5 inches and 6 pounds; that means a potentially life-threatening situation for the Chihuahua. Though the male Chihuahua may need a bit of assistance mating with a German shepherd, it's much safer, as the larger dog should have no difficulty carrying and delivering her litter.