Selegiline in Dogs

It's not the fountain of youth, but an elderly dog on selegiline can get a little extra spring in his step.
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For the dog that has Cushing's disease or is simply getting on in years, selegiline might give him a boost by promoting dopamine, a helpful chemical in Duke's bodily functions. The dosage depends on your pup, and it may take a while to see its effects.

Double-Duty Drug

Selegiline, also known as L-Deprenyl, is the generic name for Eldepryl, Anipryl and Carbex. If Duke has the hormonal imbalance known as Cushing's disease, or is showing the effects of old age or cognitive dysfunction syndrome, the vet may prescribe this pill to help manage his condition. Selegiline works with your pup's enzymes to promote the function of the chemical dopamine in his body. For the dog with Cushing's disease, selegiline is only effective if it's caused by a pituitary tumor, working for about 20 to 40 percent of dogs with the disease. Duke's issue may be he's simply getting up in years. If he's displaying disorientation or memory loss, having accidents and seems disinterested in family activities, selegiline's ability to prolong the effects of dopamine may help his symptoms. For both conditions, it may take a month or two for the medication to take effect, and the vet may need to adjust the dose.

About 5 percent of dogs have side effects such as diarrhea, vomiting, decreased appetite, tremors and other issues making selegiline intolerable. Make sure your vet knows any medications Duke takes, as selegiline can interact with other drugs.